| DATE | OPPONENT | RESULT | RECORD |
| 1/13/21 | BURGETTSTOWN | L 58-12 | 0-1 |
| 1/14/21 | PITTSBURGH CENTRAL CATHOLIC * | W 49-21 | 1-1, (1-0) |
| 1/16/21 | AVONWORTH | W 45-27 | 2-1 |
| 1/16/21 | WEST GREENE | W 46-24 | 3-1 |
| 1/18/21 | UPPER ST. CLAIR * | W 42-25 | 4-1, (2-0) |
| 1/20/21 | @ Bethel Park * | W 42-34 | 5-1, (3-0) |
| 1/21/21 | @ Jefferson-Morgan | W 45-24 | 6-1 |
| 1/25/21 | WASHINGTON | W 57-12 | 7-1 |
| 1/27/21 | MT. LEBANON * | W 44-30 | 8-1, (4-0) |
| 1/29/21 | @ Penn Hills | W 66-10 | 9-1 |
| 2/2/21 | @ Hopewell | W 45-24 | 10-1 |
| 2/8/21 | @ Waynesburg
(Section Finals) | L 66-6 | 10-2 |
| 2/10/21 | @ Seneca Valley
(WPIAL Quarterfinals) | L 60-14 | 10-3 |
| 2/11/21 | @ South Fayette | W 36-33 | 11-3 |
| 2/13/21 | @ Southmoreland | W 37-30 | 12-3 |
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